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TL1A/TNFSF15 Protein,Human

TL1A/TNFSF15 Protein,Human

货号: UA040184
价格: 560
规格: 10μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    TL1; VEGI; Tumor Necrosis Factor Ligand Superfamily Member 15; TNF Ligand-Related Molecule 1; Vascular Endothelial Cell Growth Inhibitor

  • Accession

    O95150-1

  • 表达序列

    Leu72-Leu251

  • 表达宿主

    E.coli

  • 分子量

    21kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE&RP-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 活性

    <10ng/ml

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 300mM NaCl, pH8.0

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.2022 Jul 14:13:891328.  eCollection 2022.

  • 稀释度

背景介绍

  • TNF-like cytokine 1A (TL1A) is a member of the TNF and TNF receptor superfamily. TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses. TL-1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-α and IL-1α. TL1A binds with high affinity to death receptor 3 (DR3), known as TNFRSF25. Recombinant human TL1A is a 21 kDa polypeptide of 180 amino acid residues

  • 生物活性JSON

    • Measured by its ability to induce apoptosis of TF‑1 human erythroleukemic cells. The EC50 for this effect is less than10ng/ml.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱JSON(RP-HPLC)