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DUSP6 His Tag Protein, Human

DUSP6 His Tag Protein, Human

货号: UA010908
价格: 1280
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3 (MAP kinase phosphatase 3; MKP-3)

  • Accession

    Q16828

  • 表达序列

    Met1-Thr381, with N-terminal His

  • 表达宿主

    E.coli

  • 分子量

    43kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, 2mM TCEP, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Nat Commun. 2022 Nov 5;13(1):6672.
    Int J Mol Sci. 2023 Apr 22;24(9):7690.

  • 稀释度

背景介绍

  • Dual-specific phosphatase-6 (DUSP6), also known as mitogen-activated protein kinase phosphatase-3 (MKP3), has been characterized as a negative feedback regulator of ERK1/2 signaling. It serves a specific and conserved function on the dephosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2). DUSP6 is a cytoplasmic DUSP known to catalyze the removal of phosphate groups from threonine and tyrosine residues on Erk1/2, Which belongs to a family of 25 protein phosphatases that dephosphorylate phosphotyrosine and phosphoserine/phosphothreonine residues within the same substrate.

  • 电泳JSON

    • 2μg (R: reducing condition, N: non-reducing condition).