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CD171 His Tag Protein, Human

货号: UA010895

价格: 1280

规格: 25μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

CD171,L1CAM
Accession

P32004
表达序列

Ile20-Glu1120, with C-terminal His
表达宿主

HEK293
分子量

150-180kDa (Reducing)
纯度

＞95% by SDS-PAGE
内毒素含量

<0.1EU/μg
标记

Unconjugated
标签

His Tag
性状

Lyophilized Powder
缓冲体系

PBS, pH7.4.
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1.Review Cell Adh Migr.2012 Jul-Aug;6(4):374-84. Epub 2012 Jul 1.

背景介绍

L1 cell adhesion molecule (L1CAM), also known as CD171, is a cell adhesion receptor in the immunoglobulin superfamily, which plays an important role in the development of the nervous system. L1CAM interacts with a variety of ligands. Including axon protein 1, CD9, neurocan, and integrins. The molecule is a type I transmembrane (TM) protein that contains an 1101 aa extracellular region (aa 20-1120) plus a 114 aa cytoplasmic domain (aa 1144-1257). Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy.