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NOTCH2 Fc Chimera Protein, Human

货号: UA010861

价格: 1340

规格: 25μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

NOTCH2, hN2, N2ECD
Accession

Q04721
表达序列

Leu26-Gln530, with C-terminal hIgG1 Fc
表达宿主

HEK293
分子量

85-93kDa (Reducing)
纯度

＞95% by SDS-PAGE
内毒素含量

<0.1EU/μg
标记

Unconjugated
性状

Lyophilized Powder
缓冲体系

PBS, pH7.4.
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1.Gene ID: 4853, updated on 12-Dec-2023.

背景介绍

Human Notch-2 is a 300 kDa type I transmembrane glycoprotein. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. As a receptor for the membrane-binding ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1), the ligands, activated by the released notch intracellular domain (NICD), form a transcription activator complex with RBPJ/RBPSUH to activate the division site enhancer gene.