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Nectin-1/PVRL1/CD111 Fc Chimera Protein, Human

Nectin-1/PVRL1/CD111 Fc Chimera Protein, Human

货号: UA010016
价格: 1800
规格: 50μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Poliovirus Receptor-Related Protein 1; Herpes Virus Entry Mediator C; Herpesvirus Entry Mediator C; HveC; Herpesvirus Ig-Like Receptor; HIgR; Nectin-1; CD111; PVRL1; HVEC; PRR1

  • Accession

    Q15223-1

  • 表达序列

    Gln31-Thr334, with C-terminal Human IgG1 Fc

  • 表达宿主

    HEK293

  • 分子量

    80-90kDa(reducing)

  • 纯度

    ＞95%, by SDS-PAGE under reducing conditions

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    Human Fc Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍

  • Nectin-1, also referred to as ED4, is a poliovirus receptor- related 1 protein is a part of the Nectin family. Nectin-1 endorses cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions among PVRL1/nectin-1 & PVRL4/nectin-4 and among PVRL1/nectin-1 & PVRL3/nectin-3 have been found. Nectin-1 acts as an entry receptor for herpes simplex virus & pseudorabies virus as well. Likewise, Neurite outgrowth-promoting activity has been shown by Nectin-1.

  • 生物活性JSON

    • Anti-His antibody Immobilized on CM5 Chip captured Nectin-4 His Tag, Human (Cat. No. UA010020), can bind Nectin-1 Fc Chimera, Human (Cat. No. UA010016) with an affinity constant of 0.521μM as determined in SPR assay.
    • Immobilized Nectin-4 His Tag, Human (Cat. No. UA010020) at 5μg/mL (100μL/well) can bind Nectin-1 Fc Chimera, Human (Cat. No. UA010016) with EC50 of 0.184μg/mL.

    • Protein A Chip captured Nectin-1/PVRL1/CD111 Fc Chimera, Human (Cat. No. UA010016), can bind Nectin-3/CD113 His Tag, Human (Cat. No. UA010487) with an affinity constant of 20.01μM as determined in SPR assay.

  • 电泳JSON

    • Nectin-1/PVRL1/CD111 Fc Chimera, Human ，1μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 95%.

  • ELISA

    • Immobilized Nectin-3/CD113 His Tag, Human (Cat. No. UA010487) at 2.0μg/mL (100μL/well) can bind Nectin-1/PVRL1/CD111 Fc Chimera, Human (Cat. No. UA010016) with EC50 of 5.43-10.29ng/ml.