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Nectin-2/CD112 His Tag Protein, Human

Nectin-2/CD112 His Tag Protein, Human

货号: UA010018
价格: 1800
规格: 50μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Poliovirus Receptor-Related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B; HveB; Nectin-2; CD112; PVRL2; HVEB; PRR2

  • Accession

    Q92692-2

  • 表达序列

    Gln32-Leu360, with C-terminal His Tag

  • 表达宿主

    HEK293

  • 分子量

    45-54 kDa(reducing)

  • 纯度

    ＞95%, by SDS-PAGE under reducing conditions

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍

  • Nectin Cell Adhesion Molecule 2, also known as NECTIN2, is a Ca(2+)-independent cell-cell adhesion molecule which is one of the plasma membrane components of adherens junctions. NECTIN2 takes a vital part in the establishment of homotypic as well as heterotypic cell to cell contacts. NECTIN2 is essential for resisting herpes simplex virus type 2 infection in transfected cells. NECTIN2 is also a possible target for antibody therapy of breast & ovarian cancers. NECTIN2 might be related with human longevity. Two diseases which have been associated with NECTIN2 are Herpes Simplex and Ovarian Cystic Teratoma.

  • 生物活性JSON

    • Anti-His antibody Immobilized on CM5 Chip captured Nectin-2 His Tag, Human (Cat. No. UA010018), can bind PVRIG mFc Chimera, Human (Cat. No. UA010038) with an affinity constant of 98.91 nM as determined in SPR assay.
    • PVRIG Fc Chimera, Human (Cat. No. UA010135) captured on Protein A Biosenor, can bind Nectin-2/CD112 His Tag, Human (Cat. No. UA010018) with an affinity constant of 0.30μM as determined in SPR assay.
    • Immobilized PVRIG Fc Chimera, Human (Cat. No. UA010135) at 5μg/ml (100μl/well) can bind Nectin-2/CD112 His Tag, Human (Cat. No. UA010018) with EC50 of 0.46μg/ml.

  • 电泳JSON

    • Nectin-2/CD112 His Tag, Human，2μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 95%.