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Fc γ RIIB/CD32b His Tag Protein, Human

Fc γ RIIB/CD32b His Tag Protein, Human

货号: UA020003
价格: 1800
规格: 50μg
介绍: -
其他: -
产品规格

  • 物种

    Human

  • 分子别名

    Fc γ RIIb, CD32b;Fc gamma Receptor IIB/C, CD32, CD32b,CDw32

  • Accession

    P31994-1

  • 表达序列

    Ala46-Pro217, with C-terminal His

  • 表达宿主

    HEK293

  • 分子量

    27 -30 kDa(还原状态)

  • 纯度

    ＞98%, by SDS-PAGE under reducing conditions

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍

  • IgG Fc receptor (Fc γ R) is a member of the Ig superfamily, which plays a role in activating or inhibiting immune response. Human Fc γ Rs is identified as three types: RI (CD64), RII (CD32) and RIII (CD16). Human Fc γ RII / CD32 has three genes, CD32A, B and C, respectively. CD32 is a low affinity Fc receptor. Low-affinity immunoglobulin Fc γ region receptor II-b, namely CD32b, also known as FCGR2B, FCG2, IGFR2. CD32b was expressed on B cells and myeloid dendritic cells. The co-junction of CD32b on dendritic cells inhibits maturation and prevents cell activation. CD32b may also be a target for monoclonal antibody therapy of malignant tumors.

  • 生物活性JSON

    • Anti-His antibody Immobilized on CM5 Chip captured CD32b His Tag, Human (Cat. No. UA020003), can bind IgG1-Fc (UA050001) with an affinity constant of 14.9 μM as determined in SPR assay (Biacore T200).

  • 电泳JSON

    • Fc γ RⅡb/CD32b His Tag, Human，1 μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 98%.