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Fc γ RIIB/CD32b His Tag Protein, Mouse

Fc γ RIIB/CD32b His Tag Protein, Mouse

货号: UA020015
价格: 1800
规格: 50μg
介绍: -
其他: -
产品规格

  • 物种

    Mouse

  • 分子别名

    Fc gamma RIIB , CD32b;;Fc gamma Receptor IIB/C, CD32, CD32b,CDw32

  • Accession

    P08101-1

  • 表达序列

    Thr40-Arg217, with C-terminal His

  • 表达宿主

    HEK293

  • 分子量

    33-43kDa(Reducing)

  • 纯度

    ＞95%, by SDS-PAGE under reducing conditions

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍

  • Fc γ RIIB, also known as CD32b, is a low affinity inhibitory receptor for the Fc part of the IgG molecule. It is a single-channel type I membrane protein with two IgG-like C2 (immunoglobulin-like) domains. Fc γ RIIB is expressed on B cells, macrophages, neutrophils, mast cells and bone marrow dendritic cells, and participates in B cell phagocytosis of immune complexes and regulation of antibody production. In some cases, it can promote cell apoptosis. CD32b may also be a target for monoclonal antibodies in the treatment of malignant tumors.

  • 生物活性JSON

    • Anti-His antibody Immobilized on CM5 Chip captured CD32b His Tag, Mouse (Cat. No. UA020015), can bind IgG1-Fc (UA050001) with an affinity constant of 21.59 μM as determined in SPR assay.

  • 电泳JSON

    • Fc γ RIIB/CD32b His Tag, Mouse，1μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 95%.