kDa&kDa
PBS, 5% trehalose, PH7.4
·6 months from date of receipt, -60 to -80 °C as supplied.
·about 3 days in 2 to 8 °C.
·Please avoid repeated freeze-thaw cycles.
Belghith AA, Cotter CA, Ignacio MA, Earl PL, Hills RA, Howarth MR, Yee DS, Brenchley JM, Moss B. Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates. Nat Commun. 2025 May 21;16(1):4726.
Virus-like particles (VLPs) are highly structured protein particles composed of single or multiple structural proteins of the virus. Its morphological structure is similar to that of natural virus particles, does not contain virus accounting, and has strong immunogenicity and biological activity. The empty shell structure of most VLP is icosahedral or helical structure, which is composed of several specific structural proteins. At present, it is widely used in vaccine production and antigen presentation.
1μg (R: reducing condition).
Immobilized p55 Gag-VLP at 5.0μg/mL (100μL/well) can bind Anti-HIV1 p24 antibody with EC50 of 31.57-42.51ng/mL.
The mean peak Radius of VLP is 120-180 nm with more than 95% intensity as determined by dynamic light scattering (DLS)
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