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Human GST-π, His tag

Human GST-π, His tag

货号: S0A0057
价格: 250
规格: 10μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    GST class-pi, GSTP1-1, FAEES3, GST3
  • Accession

    P09211
  • 表达宿主

    E.coli
  • 分子量

    Theoretical:25.0 kDa Actual:25.0kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <1EU/mg
  • 标签

    with C-10*His
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • The Glutathione S-transferase π (GST) family of enzymes is a group of typical Phase II detoxification enzymes and is found in many prokaryotes and eukaryotes. Of these enzymes, GSTπ catalyzes the conjunction between GSH and its electrophilic substrates upon exposure to damaging free radicals. Besides metabolite detoxification, GSTπ also exhibits ligand-binding properties that initiate cellular apoptosis when triggered by cellular stress. Further research has also demonstrated that GSTπ is expressed abundantly in tumor cells and associated closely to carcinogenesis, tumor formation, and chemotherapy resistance.