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Claudin 18.2 Recombinant Rabbit mAb (Cy5 Conjugate) (SDT-102-24)

Claudin 18.2 Recombinant Rabbit mAb (Cy5 Conjugate) (SDT-102-24)

货号: S0B0065
价格: 1056
规格: 25μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    Claudin 18.2
  • 分子别名

    CLDN18.2
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Cytoplasm, Cell membrane
  • Accession

    P56856-2
  • 克隆号

    SDT-102-24
  • 应用

    IF
  • 反应种属 ?

    Hu, Ms, Rt
  • 纯化方式

    Protein A
  • 浓度

    2 mg/ml
  • 标记

    Cy5
  • 性状

    Liquid
  • 缓冲体系

    PBS, 0.1% BSA, 0.01% Proclin 300
  • 储存条件

    12 months from date of receipt / reconstitution, 4 °C as supplied.

稀释度
应用 稀释度
IF 1:100
背景介绍
  • Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. Claudin 18.2 is involved in tumor development and progression and located in the outer cell membrane. It has exposed extracellular loops and is available for monoclonal antibody binding.

  • 免疫细胞化学

    • IF shows positive staining in paraffin-embedded human stomach. Anti-Claudin 18.2 (Cy5 Conjugate) antibody was used at 1/100 dilution (magenta). Counterstained with DAPI (Blue). Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IF staining protocol.
    • IF shows positive staining in paraffin-embedded mouse stomach. Anti-Claudin 18.2 (Cy5 Conjugate) antibody was used at 1/100 dilution (magenta). Counterstained with DAPI (Blue). Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IF staining protocol.
    • IF shows positive staining in paraffin-embedded rat stomach. Anti-Claudin 18.2 (Cy5 Conjugate) antibody was used at 1/100 dilution (magenta). Counterstained with DAPI (Blue). Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IF staining protocol.