您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Human IgG2 Fc

Human IgG2 Fc

货号: S0A0053
价格: 250
规格: 10μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    Ig gamma-2 chain C region, Ig gamma-2 chain C region DOT, Ig gamma-2 chain C region TIL, Ig gamma-2 chain C region ZIE
  • Accession

    P01859
  • 表达序列

    Protein sequence(P01859, Glu99-Lys326(V161M, S257A), no tag) ERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGMEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

  • 表达宿主

    HEK293
  • 分子量

    Theoretical:25.7kDa Actual:30kDa
  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg
  • 标签

    N/A
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4.
  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).

  • 生物活性JSON

    • Immobilized Human IgG2 Fc at 20 μg/mL (50 μL/well) can bind Staphylococcus aureus Protein A (B), His tag (Cat. No. S0A0109) with EC50 of 12.95-15.57 ng/ ml.

  • 电泳JSON

    • 2μg(R: reducing conditions)