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Invivo anti-mouse Ly6G/Ly6C (Gr-1) (S-R425)

Invivo anti-mouse Ly6G/Ly6C (Gr-1) (S-R425)

货号: S0B0838
价格: 1000
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 抗原名称

    Mouse Ly-6G/Ly-6C (Gr-1)
  • 分子别名

    Lymphocyte antigen 6G, Ly-6G.1
  • 细胞定位

    Cell membrane
  • Accession

    P35461
  • 克隆号

    S-R425
  • 抗体类型

    Recombinant mAb
  • 抗体同种型

    Rat IgG2b,k
  • 应用

    in vivo depletion of Gr-1+ myeloid cells
  • 反应种属 ?

    Ms
  • 纯化方式

    Protein G
  • 浓度

    5 mg/ml
  • 内毒素含量

    <1EU/mg
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;

    -20 °C for 3 months under sterile conditions; 

    -80 °C for 24 months under sterile conditions.

    Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • This antibody recognizes the same epitope as clone RB6-8C5. Ly-6G protein is a GPI (glycosylphosphatidylinositol)-anchored protein. Ly-6G is primarily expressed on monocytes, neutrophils, and T cells. It plays a crucial role in inhibiting anti-tumor efficacy and T-cell responses. Due to its specific expression on neutrophils, Ly-6G has been widely used as a surface marker in flow cytometry, cell sorting, and immune phenotyping experiments. Unique expression of Ly-6G in bone marrow indicates its involvement in hematopoietic microenvironment, potentially regulating the development or function of immune cells within the bone marrow niche.