12 months from date of receipt / reconstitution, -20 °C as supplied
| 应用 | 稀释度 |
|---|---|
| Dot Blot | 1:1000 |
| WB | 1:1000 |
LRRK2, also known as Leucine-rich repeat kinase 2, is a large, multi-domain protein kinase that belongs to the ROCO (Ras of complex proteins) family. It is highly conserved across species and plays important roles in various cellular processes, including vesicle trafficking, autophagy, and cytoskeletal dynamics. Mutations in the LRRK2 gene have been linked to several neurodegenerative disorders, most notably Parkinson's disease. The phosphorylation of LRRK2 at S935 has been implicated in modulating its kinase activity and may contribute to the pathogenesis of Parkinson's disease and other LRRK2-related disorders.
WB result of LRRK2 (phospho S935) Recombinant Rabbit mAb
Primary antibody: LRRK2 (phospho S935) Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: GFP-His LRRK2 lysate 5 ug
Lane 2: GFP-His LRRK2 S910A lysate 5 ug
Lane 3: GFP-His LRRK2 S935A lysate 5 ug
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 313 kDa
Observed MW: 280 kDa
您现在的位置：