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TIMP-2 Protein, Human

货号: UA040240

价格: 1180

规格: 10μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

CSC-21K,TIMP2
Accession

P16035
表达序列

Cys27-Pro220, with C-terminal His Tag
表达宿主

HEK293
分子量

22-24 kDa (Reducing)
纯度

＞95% by SDS-PAGE and HPLC.
内毒素含量

<0.1EU/μg
活性

Test in progress.
标记

Unconjugated
标签

His Tag
性状

Lyophilized Powder
缓冲体系

PBS, 5% trehalose, PH7.4
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1、Sci Rep . 2021 Jan 13;11(1):1071.

背景介绍

TIMP metallopeptidase inhibitor 2 is also known as TIMP2, which belongs to the protease inhibitor I35 (TIMP) family. The total length of TIMP-2 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of 22-24 kDa. TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular responses to growth factors.