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Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. Interleukin 1 induces the synthesis of the acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein.
The purity of IL-1RAcP/IL-1R3 His Tag, Cynomolgus/Rhesus macaque is more than 95% determined by SEC-HPLC.
Immobilized IL-1RAcP/IL-1R3 His Tag, Cynomolgus/Rhesus macaque(Cat. No. UA010939) at 2.0μg/mL (100μL/well) can bind IL-1RAcP Antibody (D-5) with EC50 of 0.092-0.11 μg/mL.