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CLDN7 Recombinant Rabbit mAb (SDT-077-17)

CLDN7 Recombinant Rabbit mAb (SDT-077-17)

货号: S0B2032
价格: 260
规格: 10μl
介绍: -
其他: -
产品规格
  • 宿主来源

    Rabbit
  • 抗原名称

    CLDN7
  • 分子别名

    CEPTRL2, CPETRL2, Claudin-7, Claudin 7
  • 免疫原

    Synthetic Peptide
  • 细胞定位

    Intracellular
  • Accession

    O95471
  • 克隆号

    SDT-077-17
  • 抗体类型

    Rabbit mAb
  • 应用

    IHC-P
  • 反应种属 ?

    Hu, Ms
  • 纯化方式

    Protein A
  • 浓度

    0.5mg/ml
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, -20 °C as supplied

稀释度
应用 稀释度
IHC-P 1:2000
背景介绍
  • Claudin is a transmembrane protein with four transmembrane domains. Claudin-7 (Cldn7) is a member of the claudin family, and its basic function is to maintain cell polarity and form tight junctions. CLDN7 has a full-length form (211 amino acids) and a C-terminal truncated form (158 amino acids). Recent studies have shown that low expression of the Cldn7 protein is found in a variety of malignant tumors, such as lung cancer, breast cancer, pancreatic cancer, and colorectal cancer (CRC).

  • 免疫组化

    • IHC shows positive staining in paraffin-embedded human colon cancer.

      Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human endometrial cancer.

      Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human breast cancer.

      Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded human colon.

      Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows positive staining in paraffin-embedded mouse colon.

      Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    • IHC shows negative staining in paraffin-embedded human renal clear cell carcinoma.

      Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.

      Counterstained with hematoxylin.

      Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.