您现在的位置: 首页   -  产品中心   -  免疫学   -   抗体
Human NKX6.1, His tag

Human NKX6.1, His tag

货号: S0A6012
价格: 500
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    Homeobox protein NK-6 homolog A
  • Accession

    P78426
  • 表达序列

    Protein sequence(P78426, Met1-Pro48&Thr66-Pro120&Pro179-Arg240, with C-10*His)
    MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPGGSGGSTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPGGSGGSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRGGGGSHHHHHHHHHH

  • 表达宿主

    HEK293
  • 分子量

    Theoretical: 19.4kDa Actual: 20-35kDa
  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg
  • 标记

    Unconjugated
  • 性状

    Lyophilized Powder
  • 缓冲体系

    Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
  • 溶解方法

    Reconstitute no more than 0.1 mg/mL according to the size in deionized water after rapid centrifugation.
  • 储存条件

    • 12 months from date of receipt, -20 ℃ to -70 °C as supplied.
    • 1 month, 2 to 8 °C under sterile conditions after reconstitution.  
    • Please avoid repeated freeze-thaw cycles. 
  • 稀释度

背景介绍
  • Homeobox protein NKX6.1 is a transcription factor (TF) that plays a critical role in pancreatic β cell function and proliferation. In human pancreatic islet, NKX6.1 expression is exclusive to β cells and is undetectable in other islet cells. As a Transcription factor, NKX6.1 binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.

  • 电泳JSON

    • 2μg (R: reducing conditions)