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Invivo anti-mouse VEGFR-2 Recombinant mAb

Invivo anti-mouse VEGFR-2 Recombinant mAb

货号: S0B0693
价格: 800
规格: 1mg
介绍: -
其他: -
产品规格
  • 宿主来源

    Rat
  • 分子别名

    Vascular endothelial growth factor receptor 2, Fetal liver kinase 1 (FLK-1), Kinase NYK, Protein-tyrosine kinase receptor flk-1, CD309, Kdr, Flk-1, Flk1
  • Accession

    P35918
  • 克隆号

    DC101
  • 抗体类型

    Rat mAb
  • 应用

    in vitro blocking of VEGFR signaling, in vivo blocking of VEGF/VEGFR-2 signaling, WB
  • 反应种属 ?

    Ms
  • 纯化方式

    Protein G
  • 浓度

    5 mg/ml
  • 内毒素含量

    <1EU/mg
  • 标记

    Unconjugated
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, containing no preservative

  • 储存条件

    2 to 8 °C for 2 weeks under sterile conditions;

    -20 °C for 3 months under sterile conditions; 

    -80 °C for 24 months under sterile conditions.

    Please avoid repeated freeze-thaw cycles.

稀释度
应用 稀释度
WB 1:500
背景介绍
  • VEGFR-2 protein, also known as Vascular Endothelial Growth Factor Receptor 2 (VEGFR2 or KDR), is a crucial type III receptor tyrosine kinase that plays a pivotal role in regulating angiogenesis, vascular development, permeability, and embryonic hematopoiesis. Specifically, VEGFR-2 is a cell surface receptor for VEGFA, VEGFC, and VEGFD. It actively promotes endothelial cell proliferation, survival, migration, differentiation, and actin cytoskeleton reorganization. Furthermore, VEGFR-2 mediates VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, which are essential processes in vasculogenesis and angiogenesis.

  • 免疫印迹

    • WB result of Invivo anti-mouse VEGFR-2 Recombinant mAb
      Primary antibody: Invivo anti-mouse VEGFR-2 Recombinant mAb at 1/500 dilution
      Lane 1: Mouse VEGFR-2/Flk-1/KDR Fc Chimera Protein 0.5 µg
      Lane 2: Mouse VEGFR-2/Flk-1/KDR Fc Chimera Protein 1 µg
      Secondary antibody: Goat Anti-rat IgG, (H+L), HRP conjugated at 1/1000 dilution
      Predicted MW: 150 kDa
      Observed MW: 130~180 kDa