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BTLA His Tag Protein, Mouse

BTLA His Tag Protein, Mouse

货号: UA010627
价格: 2800
规格: 100μg
介绍: -
其他: -
产品规格
  • 物种

    Mouse
  • 分子别名

    CD272
  • Accession

    Q32MV9
  • 表达序列

    Glu30-Gly176, with C-terminal 10*His

  • 表达宿主

    HEK293
  • 分子量

    30-45kDa

  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. DDEL RIO ML, KAYE J, RODRIGUEZ BARBOSA JI. Detection of protein on BTLAlow cells and in vivo antibody-mediated down-modulation of BTLA on lymphoid and myeloid cells of C57BL/6 and BALB/c BTLA allelic variants.[J]. Immunobiology: Zeitschrift fur Immunitatsforschung, 2010 ,215(7):570-578.

  • 稀释度

背景介绍
  • B-and T-lymphocyte attenuator (BTLA) is also known as B-and T-lymphocyte-associated protein, CD antigen CD272. BTLA is a inhibitory molecule which belongs to the Ig superfamily that attenuates BCR and TCR-mediated signaling, and thereby functions as a negative regulator of lymphocyte activation. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells.

  • 电泳JSON

    • 2μg (R: reducing conditions, N: non-reducing conditions).

  • ELISA

    • Immobilized BTLA His Tag Protein, Mouse (Cat. No. UA010627) at 2.0μg/mL (100μL/well) can bind BTLA/CD272 Recombinant Rabbit mAb (S-742-13) (Cat. No. S0B0668) with EC50 of 0.54-0.70 ng/ mL.