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KIR2DL5/CD158f Fc Chimera Protein, Human

货号: UA010631

价格: 2784

规格: 100μg

介绍: -

其他: -

产品规格

物种

Human
分子别名

CD158f
Accession

Q8N109
表达序列

His22-His240, with C-terminal Human IgG1 Fc
表达宿主

HEK293
分子量

60-72kDa (Reducing)
纯度

＞95% by SDS-PAGE
内毒素含量

<0.1EU/μg
标记

Unconjugated
标签

Human Fc Tag
性状

Lyophilized Powder
缓冲体系

PBS, pH7.4.
溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用

1.Estefania, E. et al. (2007) J. Immunol. 178:4402. 2.Lanier, L. L. (2005) Annu. Rev. Immunol. 23:225.

背景介绍

Killer cell immunoglobulin-like receptor 2DL5(KIR2DL5), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells.KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells to sense self-HLA.KIR2DL5 is encoded by two paralogous genes displaying copy number variation and allelic polymorphism-KIR2DL5A and KIR2DL5B. Functional polymorphisms in both its promoter and its coding regions are critical for understanding the KIR2DL5 role in immunity and its importance for human health.