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Biotinylated BCMA/TNFRSF17 His&Avi Tag Protein, Cynomolgus

Biotinylated BCMA/TNFRSF17 His&Avi Tag Protein, Cynomolgus

货号: UA010764
价格: 2800
规格: 25μg
介绍: -
其他: -
产品规格

  • 物种

    Cynomolgus

  • 分子别名

    TNFRSF17, CD269, BCM

  • Accession

    XP_005591343.1

  • 表达序列

    Met1-Ala53, with C-terminal His and Avi Tag

  • 表达宿主

    HEK293

  • 分子量

    15-20kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    Avi Tag, His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Gene ID: 608, updated on 18-Aug-2023.

  • 稀释度

背景介绍

  • B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).

  • ELISA

    • Immobilized Biotinylated BCMA/TNFRSF17 His&Avi Tag, Cynomolgus (Cat. No. UA010764) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Anti-Human BCMA Monoclonal Antibody (Belantamab) with EC50 of 1.44-1.79 ng/ml.