Asp24-Ser530 with His Tag at C-Terminus
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1.Song, H.H. and J. Filmus (2002) Biochim. Biophys. Acta 1573:241.
2.Fransson, L-A. et al. (2004) Cell. Mol. Life Sci. 61:1016.
3.De Cat, B. and G. David (2001) Semin. Cell Dev. Biol. 12:117.
4.Lamoureux, F. et al. (2007) BioEssays 29:758.
Glypicans, a small multigene family of glycosylphosphatidylinositol (GPI)-linked proteoglycans, play a pivotal role in growth factor signaling. GPC-1, a member of the glypican family, is expressed in various cell types including neurons, smooth and skeletal muscle cells, keratinocytes, osteoblasts, Schwann cells, immature dendritic cells, tumor cells, and tumor-associated vascular endothelial cells. The glypican-related integral membrane proteoglycan family (GRIPS) consists of core proteins anchored to the plasma membrane via a glycosyl phosphatidylinositol linkage. These proteins are implicated in the regulation of cell division and growth control.
1μg (R: reducing condition, N: non-reducing condition).
The purity of Glypican 1/GPC1(S486A, S488A, S490A) His Tag Protein, Human is more than 95 % as determined by SEC-HPLC.