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MMP-9 His Tag Protein, Mouse

MMP-9 His Tag Protein, Mouse

货号: UA011153
价格: 2280
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Mouse
  • 分子别名

    MMP9, CLG4B, GELB, MANDP2, Gelatinase B
  • Accession

    P41245
  • 表达序列

    Ala20-Pro730 with His Tag at C-Terminus

  • 表达宿主

    HEK293
  • 分子量

    80-95kDa (Reducing)
  • 纯度

    > 95% by SDS-PAGE & SEC-HPLC
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, PH7.4, 5% trehalose
  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
    · Please avoid repeated freeze-thaw cycles.

  • 稀释度

背景介绍
  • Matrix metalloproteinase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B (GELB), or CLG4B, is secreted by neutrophils, macrophages, and various transformed cells. It is the most complex member of the MMP family in terms of domain structure and activity regulation.
    Structurally, MMP-9 can be divided into five distinct domains: a prodomain that is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain with the zinc-binding site, a proline-rich linker region, and a carboxyl-terminal hemopexin-like domain. This enzyme degrades various substrates, including gelatin, collagen types IV and V, and elastin.
    MMP-9 is implicated in a variety of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis, and is considered a potential therapeutic target

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱JSON(SEC-HPLC)

    • The purity of MMP-9 His Tag Protein, Mouse is more than 95 % as determined by SEC-HPLC.