Met33-Asp320 with Human IgG1 Fc Tag at the C-terminus
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1. Wang, Han et al.Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.Cell.Volume 164;Issue 1:258 - 268
Ebola virus glycoprotein (GP1), acting as a receptor-binding subunit, is crucial for the virus entry process. In the late stages of infection, GP1 downregulates key host cell surface molecules, including integrins such as ITGA1-6, which can disrupt cell adhesion and potentially lead to compromised vascular integrity.
1μg (R: reducing condition).
The purity of Glycoprotein/GP RBD hFc chimera protein, Ebola virus-Q7T9D9 is more than 90% determined by SEC-HPLC.
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