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TPBG/5T4 His Tag Protein, Human

TPBG/5T4 His Tag Protein, Human

货号: UA011109
价格: 1280
规格: 25μg
介绍: -
其他: -
产品规格
  • 物种

    Human
  • 分子别名

    TPBG,5T4, M6P1,5T4AG, WAIF1 ,5T4 oncofetal trophoblast glycoprotein
  • Accession

    Q13641
  • 表达序列

    Ser32-Ser355 with His tag at the C-Terminus

  • 表达宿主

    HEK293
  • 分子量

    50-72kDa (Reducing)
  • 纯度

    >95% by SDS-PAGE & SEC-HPLC
  • 活性

    Immobilized TPBG/5T4 His Tag Protein, Human (Cat. No. UA011109) at 2.0μg/mL (100μL/well) can bind TPBG Recombinant Monoclonal Antibody with EC50 of 1.26-2.59ng/mL.
  • 标记

    Unconjugated
  • 标签

    His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, PH7.4, 5% trehalose
  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Li F, Wang Y, Cao J, Chen Q, Gao Y, Li R, Yuan L. Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis. Front Pharmacol. 2024 Jun 20; 15:1388205.

  • 稀释度

背景介绍
  • Trophoblast glycoprotein (TPBG), also known as 5T4, is a therapeutic target for several anticancer agents in clinical development. This is primarily due to its high expression in tumors and low expression in normal adult tissues. The TPBG gene encodes a leucine-rich transmembrane glycoprotein that may play a role in cell adhesion. TPBG is expressed by all types of trophoblasts as early as the ninth week of development.

  • 电泳JSON

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱JSON(SEC-HPLC)

    • The purity of TPBG/5T4 His Tag Protein, Human is more than 95% determined by SEC-HPLC.

  • ELISA

    • Immobilized TPBG/5T4 His Tag Protein, Human (Cat. No. UA011109) at 2.0μg/mL (100μL/well) can bind TPBG Recombinant Monoclonal Antibody with EC50 of 1.26-2.59ng/mL.