Glu27-Lys101 with His Tag at C-Terminus
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Maguire, J. J. & Davenport, A. P. Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. Br. J. Pharmacol. 171, 5555–5572 (2014)
Davenport, A. P. et al. Endothelin. Pharmacol. Rev. 68, 357–418 (2016).
Endothelin receptors, specifically ETA and ETB, are class A G protein-coupled receptors (GPCRs) that are activated by the vasoactive peptide endothelins and play a role in blood pressure regulation. Selective signaling through the ETB receptor induces vasorelaxation, making selective ETB agonists potential candidates for improved anti-tumor drug delivery and neuroprotection.
2μg (R: reducing condition, N: non-reducing condition).
The purity of Endothelin B Receptor His Tag Protein, Human is more than 95% determined by SEC-HPLC.
Immobilized Endothelin B Receptor His Tag Protein, Human (Cat. No. UA011142) at 2.0μg/mL (100μL/well) can bind EDNRB Rabbit pAb with EC50 of 6.38-8.77ng/mL.