Leu25-Glu176
18 kDa (Reducing)
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Annu Rev Immunol. 2011:29:71-109.
Interleukin-20 (IL-20) is a member of the IL-10 cytokine family that plays a role in regulating inflammatory and immune responses. In humans, IL-20 is produced by activated monocytes, keratinocytes, and other cell types in response to pro-inflammatory stimuli. IL-20 signals through a receptor complex composed of IL-20R1 and IL-20R2 subunits, leading to the activation of downstream signaling pathways, including the JAK-STAT pathway. IL-20 has been implicated in various inflammatory conditions, including psoriasis, rheumatoid arthritis, and inflammatory bowel disease. It exerts its biological effects by promoting the production of pro-inflammatory cytokines, chemokines, and matrix metalloproteinases, contributing to tissue inflammation and remodeling.
2μg (R: reducing condition, N: non-reducing condition).
您现在的位置：
